Browsing by Author "Jacobson, Lee Stuart"
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Cathepsin-dependent lysosome rupture controls cell death, Nalp3 impairment, and adaptive immunity by the adjuvants alum and Leu-Leu-OMe
(ProQuest Dissertations & Theses, 2013)Modern, antigen-based vaccines depend on immunostimulatory compounds, known as adjuvants, to generate strong and protective adaptive immune responses. Despite the ubiquitous importance of adjuvants to modern medicine, few ...