Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.12202/4359
Title: | Re-evaluating the Role of the piRNA Pathway in Germline Development in Drosophila. |
Other Titles: | Thesis submitted in partial fulfillment of the requirements of the Jay and Jeanie Schottenstein Honors Program, Yeshiva College, Yeshiva University, May 2018. |
Authors: | Borck, Jacob J. |
Keywords: | piRNA pathway germline development RNAi pathway Drosophila somatic stem cell development |
Issue Date: | May-2018 |
Publisher: | Yeshiva College. Yeshiva University. |
Citation: | Re-evaluating the Role of the piRNA Pathway in Germline Development in Drosophila. Borck, Jacob J. Thesis submitted in partial fulfillment of the requirements of the Jay and Jeanie Schottenstein Honors Program, Yeshiva College, Yeshiva University, May 2018. |
Abstract: | The piRNA pathway has previously been shown to play a vital role in germline development in Drosophila through transposon repression. Through individualization complex staining and scoring techniques, fertility tests, and cytological analysis, this thesis focuses on expanding the understanding of the role of the piRNA pathway to include contributions to somatic stem cell development and to show the involvement of the RNAi pathway in spermatogenesis as well. A functional redundancy between the piRNA and RNAi pathways has been uncovered through these experiments as a result of an enhanced phenotype caused by simultaneous mutations in both pathways. |
Description: | The file is restricted for YU community access only. Mentor: Josefa Steinhauer, Ph.D., Department of Biology |
URI: | https://hdl.handle.net/20.500.12202/4359 https://ezproxy.yu.edu/login?url=https://repository.yu.edu/handle/20.500.12202/4359 |
Appears in Collections: | Jay and Jeanie Schottenstein Honors Student Theses |
Files in This Item:
File | Description | Size | Format | |
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Jacob Borck Senior Honors Thesis 2018.pdf Restricted Access | PDF Rynhold OCR | 1.85 MB | Adobe PDF | View/Open |
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