Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.12202/4359
Title: Re-evaluating the Role of the piRNA Pathway in Germline Development in Drosophila.
Other Titles: Thesis submitted in partial fulfillment of the requirements of the Jay and Jeanie Schottenstein Honors Program, Yeshiva College, Yeshiva University, May 2018.
Authors: Borck, Jacob J.
Keywords: piRNA pathway
germline development
RNAi pathway
Drosophila
somatic stem cell development
Issue Date: May-2018
Publisher: Yeshiva College. Yeshiva University.
Citation: Re-evaluating the Role of the piRNA Pathway in Germline Development in Drosophila. Borck, Jacob J. Thesis submitted in partial fulfillment of the requirements of the Jay and Jeanie Schottenstein Honors Program, Yeshiva College, Yeshiva University, May 2018.
Abstract: The piRNA pathway has previously been shown to play a vital role in germline development in Drosophila through transposon repression. Through individualization complex staining and scoring techniques, fertility tests, and cytological analysis, this thesis focuses on expanding the understanding of the role of the piRNA pathway to include contributions to somatic stem cell development and to show the involvement of the RNAi pathway in spermatogenesis as well. A functional redundancy between the piRNA and RNAi pathways has been uncovered through these experiments as a result of an enhanced phenotype caused by simultaneous mutations in both pathways.
Description: The file is restricted for YU community access only. Mentor: Josefa Steinhauer, Ph.D., Department of Biology
URI: https://hdl.handle.net/20.500.12202/4359
https://ezproxy.yu.edu/login?url=https://repository.yu.edu/handle/20.500.12202/4359
Appears in Collections:Jay and Jeanie Schottenstein Honors Student Theses

Files in This Item:
File Description SizeFormat 
Jacob Borck Senior Honors Thesis 2018.pdf
  Restricted Access
PDF Rynhold OCR1.85 MBAdobe PDFThumbnail
View/Open


This item is licensed under a Creative Commons License Creative Commons