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Therapeutic Targeting of the Interleukin 1 Receptor Accessory Protein (IL1 RAP) Reveals Novel Oncogenic Functions in Acute Myeloid Leukemia
(ProQuest Dissertations & Theses Global, 2018)
Leukemia stem cells (LSC) are the defective counterparts of hematopoietic stem and progenitor cells (HSPC) that can give rise to acute myeloid leukemia (AML). LSC have been implicated as drivers of relapse in AML as they ...