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Now showing items 3747-3766 of 8387
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'I'm right.' 'No, I'm right.' New techniques for medicating high-conflict disputes
(ALM, 2021-06-22)Bill Eddy and his co-author, Michael Lomax, in their new book, "Mediating High Conflict Disputes," remind us that a mediator must be willing to cut off reflections about who pushed whom first, and instead, focus on how to ... -
I. PYROLYSIS OF DIBENZOTROPILIDENE. II. BICYCLOBUTANE-COUPLING CONSTANTS
(ProQuest Dissertations & Theses, 1976) -
Ice-binding proteins are tailored to the organism’s needs
(2021-05-24) -
Identification and analysis of renal quantitative traits loci (QTL)
(ProQuest Dissertations & Theses, 2007)Genetic variation among normal individuals leads to significant anatomical and physiological differences accounting for predisposition to renal diseases. The fate of kidney cells in response to cellular stress may determine ... -
Identification and characterization of a DNA binding protein, NF-HB (BSAP), a regulatory element in the immunoglobulin heavy chain locus
(ProQuest Dissertations & Theses, 1993)One approach to understand the molecular mechanisms that control Ig H chain gene class switching has been to utilize the DNA sequences involved in the process for selection of key trans-acting protein factors. By using ... -
Identification and characterization of a nuclear export signal in INI1/hSNF5, a component of the human SWI /SNF chromatin remodeling complex
(ProQuest Dissertations & Theses, 2001)INI1 (Integrase Interactor 1)/hSNF5 is a component of the mammalian SWI/SNF complex which acts to remodel chromatin. It was originally identified through its binding interaction with HIV-1 integrase, and has been shown to ... -
IDENTIFICATION AND CHARACTERIZATION OF AN I-J INTERACTING MOLECULE
(ProQuest Dissertations & Theses, 1987)In recent years, immunologists have begun to understand the mechanism of T-helper (Th)-cell activation: T-cell receptors on Th cells, Ia molecules on accessory cells, and foreign antigen interact in a trimolecular complex ... -
Identification and characterization of an SH2 -ANK repeat tyrosine kinase in Drosophila melanogaster
(ProQuest Dissertations & Theses, 1994)Tyrosine kinases play critical roles in the processing of developmental information. In an attempt to more clearly understand how tyrosine kinases function in these processes a molecular search for tyrosine kinases was ... -
Identification and characterization of cellular proteins which interact with adenovirus E3-14.7KDa protein, an antagonist of TNF-alpha
(ProQuest Dissertations & Theses, 1996)TNF-{dollar}\alpha{dollar} is an important inflammatory cytokine which affects numerous immune responses and cellular processes. However, its signal transduction pathways are poorly understood. Adenoviruses (Ad) encode ... -
Identification and characterization of EppA as a potential substrate of DdERK2 in cAMP relay and chemotaxis of Dictyostelium
(ProQuest Dissertations & Theses, 2006)The MAP kinase DdERK2 is critical for cAMP relay and chemotaxis to cAMP and folate, but the details downstream of DdERK2 are unclear. To search for targets of DdERK2 in Dictyostelium, 32PO 43--labeled protein samples from ... -
IDENTIFICATION AND CHARACTERIZATION OF HEPADNA VIRUS ENVELOPE PROTEINS (HEPATITIS B VIRUS, WOODCHUCK, PRE-S, DUCK, OPEN READING FRAMES)
(ProQuest Dissertations & Theses, 1986)The hepadna viruses are a family of hepatotropic, DNA-containing viruses for which the human hepatitis B virus (HBV) serves as a prototype. The association of HBV infection with acute and chronic liver disease has been ... -
Identification and characterization of novel alpha 1--3 fucosyltransferases
(ProQuest Dissertations & Theses, 2004)alpha1-3 fucosyltransferases (alpha1-3 Fuc-Ts) catalyze the transfer of fucose from GDP-fucose to glycans on lipids and proteins. This leads to the creation of glycan epitopes, such as the LewisX (Le X), VIM-2 and sialyl ... -
Identification and characterization of novel Par1b substrates that contribute to epithelial cell polarity
(ProQuest Dissertations & Theses, 2015)Non-stratifying epithelia display either a columnar or hepatocytic polarity phenotype which differs in the positioning of their luminal domains, the distribution of luminal surfaces during cell divisions, and the mechanisms ... -
Identification and functional interrogation of neurodevelopmental disease genes at multigene loci
(ProQuest Dissertations & Theses, 2016)The continual discovery of new disease loci through characterization of copy number variants (CNVs) has demonstrated that structural rearrangements play a large role in neurodevelopmental disorders (NDDs). A clear understanding ... -
Identification and functional study of a novel gene (C15ORF65) in normal and malignant hematopoiesis
(ProQuest Dissertations & Theses, 2014)In a previous collaborative study, C150RF65 (also known as FLJ27352, BX648577, and hypothetical LOC 145788) was identified as a truncated fusion partner of the major histocompatibility complex (MHC) class II transactivator ... -
Identification of a cellular protein that binds to a T cell-specific element in the SL3-3 enhancer
(ProQuest Dissertations & Theses, 1993)The murine leukemia virus, SL3-3, induces T-cell lymphomas 60 to 120 days after injection into newborn mice, while the closely related virus, Akv, induces no disease. Recombination studies between these viruses have shown ... -
Identification of a genomic fragment of Mycobacterium tuberculosis contributing to in vivo growth advantage
(ProQuest Dissertations & Theses, 1993)The work presented here describes the development and testing of novel molecular tools and genetic methods that may be used to identify determinants of virulence of the pathogenic mycobacteria. The methods were used to ... -
Identification of Changes in Phosphoproteome of Mouse Spermatocytes Upon Inhibition of Sumoylation
(2021-12)Across the globe, approximately 15% of couples experience infertility issues with about 50% of cases primarily due to a male factor (Agarwal et al., 2021). While some causes of infertility have been attributed to the ... -
Identification of essential roles for N-linked carbohydrates in mouse development
(ProQuest Dissertations & Theses, 1995)It has been established that eukaryotic cells absolutely require N-linked carbohydrates for survival. However, the truncated structure Man{dollar}\sb5{dollar}GlcNAc{dollar}\sb2{dollar}Asn, in place of mature N-linked ... -
Identification of genes related to transcriptional regulation using a novel systematic yeast library
(ProQuest Dissertations & Theses, 2010)The study of transcription in yeast has led to the identification and characterization of many conserved genes that have general roles in transcriptional regulation. The genetic selections known as the Bur selection and ...
