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dc.contributor.authorReich, Batsheva
dc.descriptionThe file is restricted for YU community access only.en_US
dc.description.abstractObstructive sleep apnea, a sleep disorder known to cause airway blockage and inability to breathe during the night, has been associated with a decrease in Gammaaminobutyric acid (GABA) measured using msing proton magnetic resonance spectroscopy ( 1 H MRS) in the prefrontal cortex of the human brain, a region associated with executive function. This study aimed to obtain a fuller understanding of the mechanisms behind the human finding by investigating GABA content in the brains of hypoxic mice. Characterized by deprivation of sufficient oxygen supply, hypoxia is one of the major symptoms in obstructive sleep apnea. In fact, chronic intermittent hypoxic mouse models are often used to study aspects of obstructive sleep apnea.en_US
dc.description.sponsorshipS. Daniel Abraham Honors Programen_US
dc.publisherStern College for Womenen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.subjectMice -- Researchen_US
dc.subjectRespiratory insufficiencyen_US
dc.subjectSleep disordersen_US
dc.titleSex and age differentially affect GABAergic neurons in the mouse prefrontal cortex following chronic intermittent hypoxiaen_US

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Attribution-NonCommercial-NoDerivs 3.0 United States
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 United States