Browsing Albert Einstein College of Medicine: Doctoral Dissertations by Title
Now showing items 1087-1106 of 1674
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RABBIT ERYTHROID RIBONUCLEASES
(ProQuest Dissertations & Theses, 1975) -
RADIOIMMUNOLOGICAL STUDIES OF THYMOSIN
(ProQuest Dissertations & Theses, 1974) -
Radioimmunotherapy and antiviral therapy: An elimination strategy for HIV-infected cells
(ProQuest Dissertations & Theses, 2015)While antiretroviral therapy (ART) has dramatically improved life expectancy for people infected with HIV/AIDS, it cannot kill infected cells. These cells persist in cellular and anatomical reservoirs, leading to disease ... -
Rat carboxypeptidase E gene: Structure, expression, and regulation of expression
(ProQuest Dissertations & Theses, 1993)The gene for rat carboxypeptidase E (CPE), a neuropeptide-processing enzyme, has been cloned and partially sequenced. The entire CPE gene spans 50 kilobases and consist of nine exons, each of which contains protein-coding ... -
RAT LIVER GLUTAMYL-RNA SYNTHETASE: PURIFICATION, PROPERTIES AND EFFECT OF POLYNUCLEOTIDES
(ProQuest Dissertations & Theses, 1966) -
Rational Protein Design to Dissect Class I Viral Fusion Mechanisms
(ProQuest Dissertations & Theses, 2014)Enveloped viruses utilize surface glycoproteins to facilitate membrane fusion with a host cell in order to deliver viral genetic material, a necessary early step in the infection process. In the case of class I viruses, ... -
Re-assessing the role of the floor plate as an intermediate target for commissural axons in the embryonic mouse spinal cord
(ProQuest Dissertations & Theses, 2006)In the developing nervous system, axons navigate great distances to reach their final targets. Along their path, they encounter intermediate targets, which contain cues to guide them along the next leg of their journey. ... -
REACTIONS OF ALPHA-HALO-ALPHA,ALPHA-DIHALO-AND ALPHA-MESYLOXYKETONES WITHPHOSPHINES
(ProQuest Dissertations & Theses, 1969) -
REACTIONS OF ALPHA-HALOKETONES WITH TERTIARY ORGANOPHOSPHORUS COMPOUNDS
(ProQuest Dissertations & Theses, 1970) -
Receptor editing in a mature, autoreactive B cell population
(ProQuest Dissertations & Theses, 2004)Anergy, clonal deletion, and receptor editing are important mechanisms in maintaining tolerance in the immature B cell repertoire. While the role of receptor editing is an accepted mechanism in the immature population, ... -
Recessive mutations that activate transcription by RNA polymerase III in Saccharomyces cerevisiae
(ProQuest Dissertations & Theses, 1996)Dominant and recessive mutations in the PCF1 gene, which encodes the 131 kDa subunit of transcription factor IIIC (TFIIIC{dollar}\sb{lcub}131{rcub}),{dollar} increase transcription by RNA polymerase III (pol III) in vivo ... -
Recombinant BCG vaccines for the prevention of cancer
(ProQuest Dissertations & Theses, 2000)The anti-tuberculosis vaccine bacille Calmette-Guerin (BCG) has been administered to more than 3 billion people worldwide. Aside from its use in tuberculosis and leprosy control, BCG has been well studied for its stimulation ... -
RECONSTITUTION OF PBR322 DNA REPLICATION IN VITRO WITH PURIFIED PROTEINS
(ProQuest Dissertations & Theses, 1985)The replication of a duplex, covalently-closed supercoiled (form I) DNA as an intact molecule requires that the topology of the DNA be modulated. The role of proteins that alter DNA structure, e.g., topoisomerases and ... -
Region specific histone modifications in class switch recombination
(ProQuest Dissertations & Theses, 2005)Class switch recombination (CSR) rearranges the antibody variable (V) region from mu to one of the downstream gamma, epsilon or alpha constant (C) regions in the immunoglobulin heavy chain locus, which results in the ... -
REGULATED EXPRESSION OF HUMAN GLOBIN GENES AND NEIGHBORING SEQUENCES INTRODUCED INTO ERYTHROID AND NONERYTHROID CELLS (ACTIVATION, DNA-MEDIATED TRANSFER, NEGATIVE REGULATION, CHROMATIN DOMAINS, TAP)
(ProQuest Dissertations & Theses, 1985)The regulation of human globin genes during hemopoietic differentiation was investigated by introducing these genes into mouse erythroleukemia (MEL) cells by chromosome transfer and by DNA-mediated gene transfer (DMGT). ... -
Regulation and functions of the drosophila ID protein extra macrochaetae in neural development
(ProQuest Dissertations & Theses, 2017)The well-conserved basic helix-loop-helix (bHLH) genes encode dimeric transcription factors essential for many developmental events. The activities of tissue-specific bHLH transcription factors require their heterodimerization ... -
REGULATION BY PHOSPHORYLATION OF CAMP-DEPENDENT PROTEIN KINASE FROM BOVINE CARDIAC MUSCLE
(ProQuest Dissertations & Theses, 1977) -
Regulation of 60S ribosome biogenesis in the yeast Saccharomyces cerevisiae
(ProQuest Dissertations & Theses, 2008)The biosynthesis of 60S ribosomal subunits in Saccharomyces cerevisiae requires Tif6p, the yeast homologue of mammalian eIF6. This protein is necessary for the formation of 60S ribosomal subunits because it is essential ... -
Regulation of actin polymerization during tumor cell invasion
(ProQuest Dissertations & Theses, 2009)Tumor metastasis, the spread of cancer from a primary site to a distant organ, is the leading cause of mortality among cancer patients. For a carcinoma cell to metastasize, it must first successfully invade the basement ... -
Regulation of anti -dsDNA B lymphocytes in autoimmunity: Molecular mimicry and hormone modulation of tolerance
(ProQuest Dissertations & Theses, 2003)Anti-double stranded (ds) DNA antibodies are responsible for much of the pathology of systemic lupus erythematosus. Two mouse models in which anti-dsDNA B cells escape tolerance were used to study their regulation.;A peptide ...