Browsing Albert Einstein College of Medicine: Doctoral Dissertations by Title
Now showing items 319-338 of 1673
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Current concepts in neuropsychiatric lupus: Potential mechanisms and therapeutic avenues
(ProQuest Dissertations & Theses, 2018)The central nervous system manifestations of systemic lupus erythematosus, known as neuropsychiatric lupus (NPSLE), are categorized by two overarching phenotypes. These include focal disease that is similar to other forms ... -
CYCLIC 3',5'-ADENOSINE MONOPHOSPHATE AND THE GLUCOSE EFFECT IN BACTERIA
(ProQuest Dissertations & Theses, 1975) -
CYCLIC ADENOSINE-3'5'-MONOPHOSPHATE (CYCLIC-AMP) DEPENDENT PROTEIN KINASEFROM BEEF HEART
(ProQuest Dissertations & Theses, 1974) -
CYCLIC AMP AND GLYCOGENOLYSIS IN THE RAT CAUDATE NUCLEUS
(ProQuest Dissertations & Theses, 1977) -
CYCLIC AMP-DEPENDENT PROTEIN KINASE OF LYMPHOID TISSUE AND CULTURED MAMMALIAN CELLS
(ProQuest Dissertations & Theses, 1972) -
CYCLIC NUCLEOTIDE METABOLISM IN BLASTOCLADIELLA EMERSONII
(ProQuest Dissertations & Theses, 1975) -
CYCLIC NUCLEOTIDE METABOLISM IN CAULOBACTER CRESCENTUS
(ProQuest Dissertations & Theses, 1976) -
CYCLIC NUCLEOTIDE PHOSPHODIESTERASE FROM BEEF HEART
(ProQuest Dissertations & Theses, 1971) -
CYCLIC-AMP - DEPENDENT PROTEIN KINASE REGULATION OF SPERM MOTILITY
(ProQuest Dissertations & Theses, 1986)cAMP-dependent phosphorylation of sperm proteins has been implicated in the initiation and/or regulation of sperm motility. Since cAMP-dependent protein kinase (R(,2)C(,2)) is believed to be the sole cellular mediator of ... -
Cyclic-AMP-dependent protein kinase and a transmembrane tyrosine phosphatase in Caenorhabditis elegans: Structure, function and regulation
(ProQuest Dissertations & Theses, 1990)Protein kinases and protein phosphatases are central components of signal transduction pathways. This thesis characterized two important proteins involved in signaling in C. elegans, the regulatory subunit (R) of cAMP-dependent ... -
Cyclin D3 and Msh6 in germinal center function and lymphomagenesis
(ProQuest Dissertations & Theses, 2009)B cells generate a diverse antibody response in the context of a proliferative program in the germinal centers (GC) of secondary lymphoid organs. Although these GC B cells have mechanisms to tolerate the genotoxic stress, ... -
Cytokine gene expression after Staphylococcus aureus infection
(ProQuest Dissertations & Theses, 1996)Staphylococcus aureus (S. aureus) is a virulent pathogen capable of causing sepsis and shock. Little is known about the host response to staphylococcal bacterial infection. To identify the mechanisms involved in S. aureus ... -
Cytokine regulation of neuropeptide expression in cultured sympathetic neurons
(ProQuest Dissertations & Theses, 1992)This thesis discusses the regulation of substance P (SP) in cultured sympathetic neurons by different cytokines and compares SP to neuropeptide Y (NPY). The chapters are comprised of manuscripts submitted for publication ... -
Cytokine regulation of the expression of receptors for neurotransmitters
(ProQuest Dissertations & Theses, 1995)The synaptic properties of a neuron depend not only on its transmitter phenotype, but also on its complement of receptors for neurotransmitters. Epigenetic signals that influence the expression of receptors may regulate ... -
Cytological and genetic analysis of sexual dimorphism during meiotic prophase I in mammals
(ProQuest Dissertations & Theses, 2005)Meiosis is the cell division pathway necessary for reducing cells with a diploid chromosome number to haploid germ cells required for sexual reproduction. Chromosome reduction during meiosis is accomplished by one replicative ... -
Cytoplasmic component of the bacterial flagellar motor
(ProQuest Dissertations & Theses, 1993)Bacterial flagellar basal bodies isolated using standard protocols do not possess the proteins required for motor function. Five motor proteins have been identified to date based on genetic analysis in Escherichia coli and ... -
Cytosine methylation dynamics during normal cell differentiation
(ProQuest Dissertations & Theses, 2008)A major mediator of epigenetic regulation of gene expression in the mammalian genome is the methylation of cytosines in the context of cytosine-guanine (CG) dinucleotides. Our current appreciation of how cytosine methylation ... -
Cytoskeletal-based vesicular trafficking of the bile salt transporter, Ntcp
(ProQuest Dissertations & Theses, 2007)Intracellular trafficking and protein sorting regulate the abundance and therefore activity of transporters present at the plasma membrane. The transporter, Na+/taurocholate cotransporting polypeptide (ntcp), is known to ... -
Cytosolic carboxypeptidase 1: Tubulin processing and neurodegeneration
(ProQuest Dissertations & Theses, 2012)Purkinje cell degeneration (pcd) is a classical mouse mutant which has been used as a model of neurodegenerative disorder for decades. pcd mouse has a disruption in the gene encoding cytosolic carboxypeptidase 1 (CCP1), ... -
Deciphering neuronal dysfunction in Tau pathology
(ProQuest Dissertations & Theses, 2010)A hallmark feature of Alzheimer's disease pathology is the presence of neurofibrillary tangles (NFTs), which are intracellular aggregates of conformationally abnormal and hyperphosphorylated tau. Tau function is important ...