Browsing Albert Einstein College of Medicine: Doctoral Dissertations by Author "ESKRIDGE, ETTA MARY"
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A DIRECT DETERMINATION OF THE MINIMUM SIZE FOR A EUKARYOTIC SECRETORY PRECURSOR (PREPROINSULIN, TRANSLOCATION, SIGNAL SEQUENCE, ENDOPLASMIC RETICULUM, GENE FUSION)
ESKRIDGE, ETTA MARY (ProQuest Dissertations & Theses, 1986)Most eukaryotic secretory proteins are synthesized as precursors containing a transient amino-terminal signal peptide of 20-25 amino acids. The signal peptide mediates binding of polysomes to the endoplasmic reticulum (ER) ...