Browsing Albert Einstein College of Medicine: Doctoral Dissertations by Author "Edwards, Yasmin"
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Msh3 knock-in mouse model demonstrates novel functions of the protein in genome maintenance
(ProQuest Dissertations & Theses, 2011)Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominant cancer syndrome, caused by mutations in several of the DNA mismatch repair (MMR) genes. MutS homologue 3 (MSH3) is a member of the MMR protein ...