Browsing Albert Einstein College of Medicine: Doctoral Dissertations by Author "Ramalingam, Dhivya"
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RNA aptamers directed to the HIV-1 GAG polyprotein as inhibitors of replication and as tools to dissect replication mechanisms
(ProQuest Dissertations & Theses, 2011)The Gag polyprotein orchestrates the assembly of HIV-1 and is the only viral protein required for the formation of non-infectious virus-like particles in vitro. Gag is synthesized in the cytoplasm of HIV infected cells and ...