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    • The search for trans-acting factors affecting somatic mutation 

      Sack, Stephen Zohar (ProQuest Dissertations & Theses, 2002)
      Somatic hypermutation of immunoglobulin genes is an elusive process that causes point mutations to occur at an exceptionally high rate of 10 -4--10-3-per base pair per generation and is vital to providing immunity. We have ...