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dc.contributor.advisorSchuck, Alyssa
dc.contributor.authorHuberfeld, Alexandra
dc.date.accessioned2021-06-17T17:55:48Z
dc.date.available2021-06-17T17:55:48Z
dc.date.issued2021-04-27
dc.identifier.citationHuberfeld, A. (2021, April). The Applications of High Throughput Screening and its Value as a Drug Discovery Tool in the Pharmaceutical Industry and Academia [Bachelor's honors thesis, Yeshiva University].en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12202/6902
dc.descriptionSenior honors thesis / Open Accessen_US
dc.description.abstractHigh throughput screening is a method of drug development that has become increasingly popular in the past three decades. Since its popularization in the 1990s, it has been criticized by proponents of typical drug development strategies as costly and ineffective. This paper outlines the technique of high throughput screening, its history, and present uses. Using the design of a screen to identify small molecule activators for a sodium-citrate transporter in order to treat SLC13A5 Deficiency, the process of high throughput screening is outlined. The paper argues that while investing in the process is valuable for large pharmaceutical companies, it is not justifiable for academic researchers.en_US
dc.description.sponsorshipThe S. Daniel Abraham Honors Programen_US
dc.language.isoen_USen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subjectseniors honors thesisen_US
dc.subjecthigh throughput screeningen_US
dc.subjectdrug discovery toolen_US
dc.subjectsodium-citrate transporteren_US
dc.subjectSLC13A5 Deficiencyen_US
dc.subjectpharmaceutical companiesen_US
dc.subjectacademiaen_US
dc.titleThe Applications of High Throughput Screening and its Value as a Drug Discovery Tool in the Pharmaceutical Industry and Academiaen_US
dc.typeThesisen_US


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Attribution-NonCommercial-NoDerivs 3.0 United States
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 United States