Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.12202/6902
Title: | The Applications of High Throughput Screening and its Value as a Drug Discovery Tool in the Pharmaceutical Industry and Academia |
Authors: | Schuck, Alyssa Huberfeld, Alexandra |
Keywords: | seniors honors thesis high throughput screening drug discovery tool sodium-citrate transporter SLC13A5 Deficiency pharmaceutical companies academia |
Issue Date: | 27-Apr-2021 |
Citation: | Huberfeld, A. (2021, April). The Applications of High Throughput Screening and its Value as a Drug Discovery Tool in the Pharmaceutical Industry and Academia [Bachelor's honors thesis, Yeshiva University]. |
Abstract: | High throughput screening is a method of drug development that has become increasingly popular in the past three decades. Since its popularization in the 1990s, it has been criticized by proponents of typical drug development strategies as costly and ineffective. This paper outlines the technique of high throughput screening, its history, and present uses. Using the design of a screen to identify small molecule activators for a sodium-citrate transporter in order to treat SLC13A5 Deficiency, the process of high throughput screening is outlined. The paper argues that while investing in the process is valuable for large pharmaceutical companies, it is not justifiable for academic researchers. |
Description: | Senior honors thesis / Open Access |
URI: | https://hdl.handle.net/20.500.12202/6902 |
Appears in Collections: | S. Daniel Abraham Honors Student Theses |
Files in This Item:
File | Description | Size | Format | |
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Huberfeld Alexandra 2021 OA The Application.pdf | 1.03 MB | Adobe PDF | View/Open |
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