BIO3513D: Genetics

Abstract

Course goals and abjectives: Goal #1. Students will acquire an understanding of the laws of genetics as applied, in particular, to human beings. Objective /a. Students will demonstrate knowledge of Mendelian genetics, based on the cellular principles of mitosis and meiosis; attention will also be directed to stem cells, cancer, and cloning Objective 2a: Students will be able to extend the principles of Mendelian genetics and to understand the rationales for the exceptions to those principles. Objective Ja: Students will be exposed to multifactorial polygenic traits, linked genes, non-Mendelian genetics (e.9., imprinting; mitochondrial inheritance), and behavioral genetics Objective 4a: Students will develop an understanding ofthe progression &om rnolecular to cellular to organismal inheritance of traits Objective 5a: Students will be able to predict the outconres of genetic crosses Go*l#Z: Students will acquire an understanding of autosomes and of sex chromosomes and of chromosomal abnormalities, both chromosomal structural aberrations ctranges in chromosorne numbers Objective 2a: Students will develop an understanding of X- and Y-linked traits and of sex determination. Objective 2b: Concepts of genic imbalance, congenital abnonnalities, spontaneous abortion, and cancer induction will be discussed Goal #3: Students will acquire knowledge of chromosomal structure and replication Objective 3a: Chromosomal hierarchy, as related to degrees of condensation, and DNA complexity will be presented. Objective 36: Students will explore the dynamics of chromosomal replication, including the functioning of telomer€l$e as related to normal and cancerous cells Goal #4: The principles of genetics as applied to biotechnology will be presented. Objective 4a: Students will develop anunderstanding of biotechnological techniques based on their understandiugs of basic principles of genetics - DNA fingerprinting, PCR, DNA sequencing, DNA analyses of disease, molecular cloning, etc.