Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.12202/9629
Title: | Conjugated dienoic acid peroxides as substrates in chaetopterus bioluminescence system. |
Authors: | Zagitova, Renata I. Purtov, Konstantin V. Shcheglov, Aleksandr S. Mineev, Konstantin S. Dubinnyi, Maxim A. Myasnyanko, Ivan N. Belozerova, Olga A. Pakhomova, Vera G. Petushkov, Valentin N. Rodionova, Natalia S. Lushpa, Vladislav A. Guglya, Elena B. Kovalchuk, Sergey Kozhemyako, Valeri B. Mirza, Jeremy D. Oliveira, Anderson G. Yampolsky, Ilia V. Kaskova, Zinaida Tsarkova, Aleksandra S. 0000-0003-1752-0726 |
Keywords: | bioluminescence peroxides unsaturated fatty acids fatty acid derivatives bioimaging bioluminescence biomedical research Chaetopterus ferroptosis lipid peroxidation luciferase luciferin parchment worm |
Issue Date: | 2023 |
Publisher: | MDPI |
Citation: | Zagitova, R. I., Purtov, K. V., Shcheglov, A. S., Mineev, K. S., Dubinnyi, M. A., Myasnyanko, I. N., Belozerova, O. A., Pakhomova, V. G., Petushkov, V. N., Rodionova, N. S., Lushpa, V. A., Guglya, E. B., Kovalchuk, S., Kozhemyako, V. B., Mirza, J. D., Oliveira, A. G., Yampolsky, I. V., Kaskova, Z. M., & Tsarkova, A. S. (2023). Conjugated Dienoic Acid Peroxides as Substrates in Chaetopterus Bioluminescence System. International Journal of Molecular Sciences, 24(11), 9466. https://doi.org/10.3390/ijms24119466 |
Series/Report no.: | Int. J. Mol. Sci.;2023, 24 |
Abstract: | Biochemistry of bioluminescence of the marine parchment tubeworm Chaetopterus has been in research focus for over a century; however, the results obtained by various groups contradict each other. Here, we report the isolation and structural elucidation of three compounds from Chaetomorpha linum algae, which demonstrate bioluminescence activity with Chaetopterus luciferase in the presence of Fe2+ ions. These compounds are derivatives of polyunsaturated fatty acid peroxides. We have also obtained their structural analogues and demonstrated their activity in the bioluminescence reaction, thus confirming the broad substrate specificity of the luciferase. [ABSTRACT FROM AUTHOR] Copyright of International Journal of Molecular Sciences is the property of MDPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
Description: | Scholarly article / Open access |
URI: | https://www.mdpi.com/1422-0067/24/11/9466 https://hdl.handle.net/20.500.12202/9629 |
ISSN: | 1661-6596 |
Appears in Collections: | Stern College for Women -- Faculty Publications |
Files in This Item:
File | Description | Size | Format | |
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Oliveira 2023 OA Conjugated dienoic ijms-24-09466.pdf | 1.56 MB | Adobe PDF | View/Open |
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